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采用电泳沉积方法在钛基材表面制得羟基磷灰石(hydroxyapatite,HA)/葡萄糖复合涂层,经烧结处理得到多孔HA涂层。采用红外光谱仪、扫描电镜、X射线衍射和热重分析表征了涂层的组成、表面形貌、物相组成及热稳定性,黏结-拉伸实验测定涂层与基体的结合强度,人体模拟体液(simulated body fluid,SBF)浸泡测定涂层的生物亲合性。结果表明:经700℃烧结处理,复合涂层中的葡萄糖微粒热分解得到多孔HA涂层,孔径为2～20μm,涂层与基体的结合强度可达17.6MPa;在1.5倍SBF(各离子浓度为SBF的1.5倍)中浸泡5d后,多孔HA涂层表面碳磷灰石化,呈现良好的生物亲合性。
Abstract：Hydroxyapatite(HA)/glucose composite coating was deposited on titanium substrate by electrophoretic deposition,and then a porous HA coating was obtained by sintering.The chemical composition,surface morphology,phase composition,and thermal stability of the porous HA coating were characterized by infrared spectrometry,scanning electron microscopy,X-ray diffraction and thermogravimetric analysis.The bonding strength between the coating and substrate was measured by a stretcher shear test;the bio-affinity of the coating was determined by immersion in simulated body fluid(SBF).The results show that the pore diameter of the porous HA coating sintered at 700 ℃ is about 2-20 μm,and its bonding strength can reach 17.6 MPa.The surface of the coating is carbonate-apatite covered after immersion in 1.5 SBF(the concentrations of ions in the 1.5 SBF are 1.5 times as high as the SBF) for 5 d,indicating that it has good bio-affinity.
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基本信息:
中图分类号:TB304
引用信息:
[1]李鹏,黄紫洋,刘榕芳,等.以葡萄糖为造孔剂制备多孔羟基磷灰石涂层[J].硅酸盐学报,2009,37(11):1864-1868.
基金信息:
福建省教育厅(JA08034)资助项目
2009-11-15
2009-11-15